Publikationen

der Arbeitsgruppe am Lehrstuhl Biochemie und Physiologie der Ernährung
2021 Inhalt einblenden
Original Publications / Originalpublikationen (peer-reviewed)
  • Hoff J, Karl B, Gerstmeier J, Beekmann U, Schmölz L, Börner F, Kralisch D, Bauer M, Werz O, Fischer D, Lorkowski S*, Press AT*. Controlled release of the α-tocopherol-derived metabolite α-13′-carboxychromanol from bacterial nanocellulose wound cover improves wound healing. Nanomaterials 2021; 11(8):1939. *Contributed equally.
    DOI 10.3390/nano11081939

  • Sandgruber F, Gielsdorf A, Baur AC, Schenz B, Müller SM, Schwerdtle T, Stangl GI, Griehl C, Lorkowski S, Dawczynski C. Variability in macro- and micronutrients of 15 commercially available microalgae powders. Marine Drugs 2021; 19(6):310.
    DOI 10.3390/md19060310

  • Pace S, Zhang K, Jordan PM, Bilancia R, Wang W, Börner F, Hofstetter RK, Potenza M, Kretzer C, Gerstmeier J, Fischer D, Lorkowski S, Gilbert NC, Newcomer ME, Rossi A, Chen X, Werz O. Anti-inflammatory celastrol promotes a switch from leukotriene biosynthesis to formation of specialized pro-resolving lipid mediators. Pharmacological Research 2021; 167:105556.
    DOI 10.1016/j.phrs.2021.105556

  • Dawczynski C, Cullen PM, Schlattmann P, Lorkowski S. A study protocol of a randomized trial evaluating the effect of using defined menu plans within an intensive personal nutritional counselling program on cardiovascular risk factors: the MoKaRi (modulation of cardiovascular risk factors) trial. Contemporary Clinical Trials Communications 2021; 22:100761.
    DOI 10.1016/j.conctc.2021.100761

  • Kluge S, Schubert M, Börmel L, Lorkowski S. The vitamin E long-chain metabolite α-13'-COOH affects macrophage foam cell formation via modulation of the lipoprotein lipase system. Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids 2021; 1866(4):158875

  • Schlörmann W, Keller F, Zetzmann S, Lorkowski S, Dawczynski C, Glei M. Impact of processing degree on fermentation profile and chemopreventive effects of oat and waxy barley in LT97 colon adenoma cells. European Food Research and Technology 2021; 247(3):569-578.
    DOI 0.1007/s00217-020-03645-2

 

Original Publications / Originalpublikationen Global Burden of Disease
  • GBD 2019 Tobacco Collaborators. Spatial, temporal, and demographic patterns in prevalence of smoking tobacco use and attributable disease burden in 204 countries and territories, 1990-2019: a systematic analysis from the Global Burden of Disease Study 2019. Lancet 2021; 397(10292):2337-2360.
    DOI 10.1016/S0140-6736(21)01169-7

 

Scientific Reviews / Wissenschaftliche Übersichtsarbeiten
  • Lorkowski S. Fette auf der Anklagebank. UGBforum 2021; 3:138-141.

  • Schumacher S, Dawczynski C, Lorkowski S. Ernährung bei arterieller Hypertonie. Ärzteblatt Thüringen 2021; 32(6):19-21.
    Article includes a CME-certified questionnaire : Ärzteblatt Thüringen 2021; 32(6):28-29.

  • Wallert M, Börmel L, Lorkowski S. Inflammatory diseases and vitamin E – What do we know and where do we go? Molecular Nutrition and Food Research 2021; 65(1):e2000097.
    DOI 10.1002/mnfr.202000097
2020 Inhalt einblenden
Original Publications / Originalpublikationen (peer-reviewed)
  • Beekmann U, Zahel P, Karl B, Schmölz L, Börner F, Gerstmeier J, Werz O, Lorkowski S, Wiegand C, Fischer D, Kralisch D. Modified bacterial cellulose dressings to treat inflammatory wounds. Nanomaterials 2020; 10(12):2508.
    DOI 10.3390/nano10122508

  • Neuwirth T, Letzel AC, Tank C, Ishida K, Cyrulis M, Schmölz L, Lorkowski S, Hertweck C. Induced production, synthesis, and immunomodulatory action of clostrisulfone, a diarylsulfone from Clostridium acetobutylicum. Chemistry – A European Journal 2020; 26(68):15855-15858.
    DOI 10.1002/chem.202003500

  • Müller AK, Helms U, Rohrer C, Möhler M, Hellwig F, Glei M, Schwerdtle T, Lorkowski S, Dawczynski C. Nutrient composition of different hazelnut cultivars grown in Germany. Foods 2020; 9(11):1596.
    DOI 10.3390/foods9111596

  • Rein D, Claus M, Frosch W, März W, Lorkowski S, Webendoerfer S, Schreiner T. Changes in erythrocyte omega-3 fatty acids in German employees upon dietary advice by corporate health. Nutrients 2020; 12(11):3267.
    DOI 10.3390/nu12113267

  • Glei M. Zetzmann S, Lorkowski S, Dawczynski C, Schlörmann W. Chemopreventive effects of raw and roasted oat flakes after in vitro fermentation with human faecal microbiota. International Journal of Food Sciences and Nutrition 2020:1-13.
    DOI 10.1080/09637486.2020.1772205

  • Schlörmann W, Atanasov J, Lorkowski S, Dawczynski C, Glei M. Study on chemopreventive effects of raw and roasted β-glucan-rich waxy winter barley using an in vitro human colon digestion model. Food and Function 2020; 11(3):2626-2638.
    DOI 10.1039/c9fo03009c

  • Kluge S, Börmel L, Schubert M, Lorkowski S. Simple and rapid real-time monitoring of LPL activity in vitro. MethodsX 2020; 17:100865.
    DOI 10.1016/j.mex.2020.100865

  • Mueller SM, Dawczynski C, Wiest J, Lorkowski S, Kipp A, Schwerdtle T. Functional biomarkers for the selenium status in the MoKaRi cohort. Nutrients 2020; 12(3):676.
    DOI 10.3390/nu12030676

  • Shkodra-Pula B, Kretzer C, Jordan PM, Klemm P, Koeberle A, Pretzel D, Banoglu E, Lorkowski S, Wallert M, Höppener S, Stumpf S, Vollrath A, Schubert S, Werz O, Schubert US. Encapsulation of the dual FLAP/mPEGS-1 inhibitor BRP-187 into acetalated dextran and PLGA nanoparticles improves its cellular bioactivity. Journal of Nanobiotechnology 2020; 18:73.
    DOI 10.1186/s12951-020-00620-7

  • Beekmann U, Schmölz L, Lorkowski S, Werz O, Thamm J, Fischer D, Kralisch D. Process control and scale-up of modified bacterial cellulose production for tailor-made anti-inflammatory drug delivery systems. Carbohydrate Polymers 2020; 236:116062.
    DOI 10.1016/j.carbpol.2020.116062

  • Schubert M, Becher S, Wallert M, Maeß MB, Abhari M, Rennert K, Mosig S, Lindenmüller S, Heller R, Grün M, Lorkowski S. The PPARγ antagonist 2-chloro-5-nitro-N-phenylbenzamide (GW9662) triggers PLIN2 expression via PPARδ and induces lipogenesis and triglyceride accumulation in human THP-1 macrophages. PPARγ antagonist GW9662 triggers PLIN2 expression via PPARδ and induces lipogenesis and triglyceride accumulation in human THP-1 macrophages. Molecular Pharmacology 2020; 97(3):212-225.
    DOI 10.1124/mol.119.117887

 

Original Publications / Originalpublikationen Global Burden of Disease
  • GBD 2019 Cardiovascular Diseases Collaborators. Global burden of cardiovascular diseases and risk factors, 1990-2019: Update from the GBD 2019 Study. Journal of the American College of Cardiology 2020; 76(25):2982-3021.
    DOI 10.1016/j.jacc.2020.11.010

  • GBD 2019 Viewpoint Collaborators. Five insights from the Global Burden of Disease Study 2019. Lancet 2020; 396(10258):1135-1159.
    DOI 10.1016/S0140-6736(20)31404-5

  • GBD 2019 Diseases and Injuries Collaborators. Global burden of 369 diseases and injuries in 204 countries and territories, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019. Lancet 2020; 396(10258):1204-1222.
    DOI 10.1016/S0140-6736(20)30925-9

  • GBD 2019 Risk Factors Collaborators. Global burden of 87 risk factors in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019. Lancet 2020; 396(10258):1223-1249.
    DOI 10.1016/S0140-6736(20)30752-2

  • LBD Double Burden of Malnutrition Collaborators. Mapping local patterns of childhood overweight and wasting in 2 low- and middle-income countries, 2000-2017. Nature Medicine 2020; 26(5):750-759.
    DOI 10.1038/s41591-020-0807-6

  • GBD 2017 Cirrhosis Collaborators. Global, regional, and national burden of cirrhosis by aetiology in 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet Gastroenterology and Hepatology 2020; 5(3):245-266.
    DOI 10.1016/S2468-1253(19)30349-8

  • LBD 2017 Under-5 Mortality Colaborators. Mapping 123 million neonatal, infant and child deaths between 2000 and 2017. Nature 2019; 574(7778):353-358.
    DOI 10.1016/S0140-6736(19)30841-4

Scientific Reviews / Wissenschaftliche Übersichtsarbeiten
  • Wallert M, März W, Lorkowski S. Vitaminmangel und Ernährung: Welche Laboruntersuchungen sind sinnvoll? MMW - Fortschritte der Medizin 2020; 162(18):50-58.
    DOI 10.1007/s15006-020-4319-6
    Article includes a CME-certified questionnaire.

  • Ziegler M, Wallert M, Lorkowski S, Peter K. Vitamin E and cardiovascular diseases. Encyclopedia 2020:3228.
    https://encyclopedia.pub/3228

  • Ziegler M, Wallert M, Lorkowski S, Peter K. Cardiovascular and metabolic protection by vitamin e: a matter of treatment strategy? Antioxidants 2020; 9(10):E935.
    DOI 10.3390/antiox9100935

  • Wallert M, Kluge S, Schubert M, Koeberle A, Werz O, Birringer M, Lorkowski S. Diversity of chromanol and chromenol structures and functions: an emerging class of anti-inflammatory and anti-carcinogenic agents. Frontiers in Pharmacology 2020; 11:362.
    DOI 10.3389/fphar.2020.00362

  • Maretzke F, Lorkowski S, Egert S. Eierverzehr und kardiometabolische Erkrankungen: eine Bestandsaufnahme. Teil 1. Ernährungs Umschau 2020; 67(1):M23-M29.
    An English version of this article was published as follows: Maretzke F, Lorkowski S, Egert S. Egg intake and cardiometabolic diseases: an update. Part 1. Ernährungs Umschau 2020; 67(1):11-17.
    DOI 10.4455/eu.2020.003

  • Maretzke F, Lorkowski S, Egert S. Eierverzehr und kardiometabolische Erkrankungen: eine Bestandsaufnahme. Teil 2. Ernährungs Umschau 2020; 67(1):M23-M29
    An English version of this article was published as follows: Maretzke F, Lorkowski S, Egert S. Egg intake and cardiometabolic diseases: an update. Part 2. Ernährungs Umschau 2020; 67(2):18-23.
    DOI 10.4455/eu.2020.005
2019 Inhalt einblenden
Original Publications / Originalpublikationen (peer-reviewed)
  • Hoang NA, Richter F, Schubert M, Lorkowski S, Klotz LO, Steinbrenner H. Differential capability of metabolic substrates to promote hepatocellular lipid accumulation. European Journal of Nutrition 2019; 58(8):3023-3034.
    DOI 10.1007/s00394-018-1847-2

  • Brown P, RELISH Consortium, Zhou Y. Large expert-curated database for benchmarking document similarity detection in biomedical literature search. Database 2019; 2019:az085.
    DOI 10.1093/database/baz085.

  • Schlörmann W, Zetzmann S, Wiege B, Haase NU, Greiling A, Lorkowski S, Dawczynski C, Glei M. Impact of different roasting conditions on sensory properties and health-related compounds of oat products. Food Chemistry 2019; 307:125548.
    DOI 10.1016/j.foodchem.2019.125548

  • Schlörmann W, Zetzmann S, Wiege B, Haase NU, Greiling A, Lorkowski S, Dawczynski C, Glei M. Impact of different roasting conditions on chemical composition, sensory quality and physicochemical properties of waxy-barley products. Food and Function 2019; 10(9):5436-5445.
    DOI 10.1039/c9fo01429b

  • Wallert M, Ziegler M, Wang X, Maluenda A, Yap ML, Witt R, Giles C, Kluge S, Meikle P, Lorkowski S, Peter K. α-Tocopherol preserves cardiac function by reducing oxidative stress and inflammation in ischemia/reperfusion injury. Redox Biology 2019; 26:101292.
    DOI 10.1016/j.redox.2019.101292

  • Schutkowski A, König B, Kluge H, Hirche F, Henze A, Schwerdtle T, Lorkowski S, Dawczynski C, Gabel A, Große I, Stangl G. Changes in the metabolic footprint and intestinal microbial community in a pig model in response to dietary proteins. Journal of Nutritional Biochemistry 2019; 67:149-160.
    DOI 10.1016/j.jnutbio.2019.02.004

  • Wallert M, Bauer J, Kluge S, Schmölz L, Chen YC, Ziegler M, Searle AK, Maxones A, Schubert M, Thürmer M, Pein H, Koeberle A, Werz O, Birringer M, Peter K, Lorkowski S. The vitamin E derivative garcinoic acid from Garcinia kola nut seeds attenuates the inflammatory response. Redox Biology 2019; 24:101166.
    DOI 10.1016/j.redox.2019.101166

  • Baars T, Wohlers J, Kusche D, Rohrer C, Lorkowski S, Jahreis G. Patterns of biodynamic milk fatty acid composition explained by a climate-geographical approach. Animals 2019; 9(3):111.
    DOI 10.3390/ani9030111

  • Rohde A, Duensing A, Dawczynski C, Godemann J, Lorkowski S, Brombach C. An app to improve eating habits of adolescents and young adults (Challenge to Go): systematic development of a theory-based and target group–adapted mobile app intervention. JMIR mHealth and uHealth 2019; 7(8):e11575.
    DOI 10.2196/11575

  • Müller AKM, Schmölz L, Wallert M, Schubert M, Schlörmann W, Glei M, Lorkowski S. In vitro digested nut oils attenuate the lipopolysaccharide-induced inflammatory response in macrophages. Nutrients 2019; 11(3):503.
    DOI 10.3390/nu11030503

  • Baars T, Jahreis G, Lorkowski S, Rohrer C, Vervoort J, Hettinga K. Changes under low ambient temperatures in the milk lipodome and metabolome of mid-lactation cows after dehorning as a calf. Journal of Dairy Science 2019; 102(3):2698-2702.
    DOI 10.3168/jds.2018-15425

  • Meier T, Gräfe K, Senn F, Sur P, Stangl GI, Dawczynski C, März W, Kleber ME, Lorkowski S. Cardiovascular mortality attributable to dietary risk factors in 51 countries in the WHO European Region from 1990 to 2016: a systematic analysis of the Global Burden of Disease Study. European Journal of Epidemiology 2019; 34(1):37-55.
    DOI 10.1007/s10654-018-0473-x

  • Keller AA, Scheiding B, Breitling R, Licht A, Hemmerich P, Lorkowski S, Reissmann S. Transduction and transfection of difficult to transfect cells: Systematic attempts for the transfection of protozoa Leishmania. Journal of Cellular Biochemistry 2019; 120(1):14-27.
    DOI 10.1002/jcb.27463

 

Original Publications / Originalpublikationen Global Burden of Disease
  • LBD 2017 Under-5 Mortality Colaborators. Mapping 123 million neonatal, infant and child deaths between 2000 and 2017. Nature 2019; 574(7778):353-358.
    DOI 10.1016/S0140-6736(19)30841-4

  • Global Burden of Disease Health Financing Collaborator Network. Past, present, and future of global health financing: a review of development assistance, government, out-of-pocket, and other private spending on health for 195 countries, 1995-2050. Lancet 2019; 393(10187):2233-2260.
    DOI 10.1016/S0140-6736(19)30841-4

  • GBD 2017 Diet Collaborators. Health effects of dietary risks in 195 countries, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet 2019; 393(10184): 1958-1972.
    DOI 10.1016/S0140-6736(19)30041-8

  • GBD 2016 Neurology Collaborators. Global, regional, and national burden of neurological disorders, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet Neurology 2019; 18(5):459-480.
    DOI 10.1016/S1474-4422(18)30499-X

  • GBD 2016 Stroke Collaborators. Global, regional, and national burden of stroke, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet Neurology 2019; 18(5):439-458.
    DOI 10.1016/ S1474-4422(19)30034-1

  • GBD Self-Harm Collaborators. Global, regional, and national burden of suicide mortality 1990 to 2016: systematic analysis for the Global Burden of Disease Study 2016. British Medical Journal 2019; 364(8186):l94.
    DOI 10.1136/bmj.l94

  • GBD 2016 Dementia Collaborators. Global, regional, and national burden of Alzheimer's disease and other dementias, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet Neurology 2019; 18(1):88-106.

 

Scientific Reviews / Wissenschaftliche Übersichtsarbeiten
  • Wallert M, Schmölz L, Lorkowski S. Gastrointestinaltrakt – zentrale Bedeutung für Vitamin E-Homöostase. Pharmakon 2019; 7(2):118-124.
    DOI 10.1691/pn.20190059

  • Birringer M, Lorkowski S. Vitamin E: Regulatory role of metabolites. IUBMB Life 2019; 71(4):479-486.
    DOI 10.1002/iub.1988

  • Lorkowski S, Dawczynski C. Ernährungstherapie einer Hypercholesterolämie bei Typ-2-Diabetes-Patienten: Kernelemente und therapeutische Möglichkeiten. Diabetologe 2019; 15(1):19-29.
    DOI 10.1007/s11428-018-0425-9

 

Editorials, Comments, Short Reports, Letters to the Editor etc.

 

Book Contributions / Buchbeiträge
  • Rohde A, Dawczynski C, Brombach C, Lorkowski S. Gesundheitsförderung aus ernährungs­wissen­schaftlicher Sicht. In: Die Perspektive(n) der Gesundheitsförderung. Staats M, ed. Beltz Juventa, Weinheim 2019:234-263.

  • Kluge S, Schubert M, Schmölz L, Wallert M, Birringer M, Lorkowski S. Bioactivity of vitamin E long-chain metabolites. In: Vitamin E in Human Health: Requirements and roles across the lifespan. Weber P, Birringer M, Blumberg, H, Eggersdorfer M, Frank J, eds. Humana Press, Heidelberg 2019:61-79.
    DOI 10.1007/978-3-030-05315-4
2018 Inhalt einblenden
Original Publications / Originalpublikationen (peer-reviewed)
  • Dugandžić V, Drikermann D, Ryabchykov O, Undisz A, Vilotijević I, Lorkowski S, Boklitz TW, Matthäus C, Weber K, Cialla-May D, Popp J. SERS-Detection of the uptake of mannose-modified nanoparticles by macrophages in vitro - a model for detection of vulnerable atherosclerotic plaques. Journal of Biophotonics 2018; 11(12): e201800013.
    DOI 10.1002/jbio.201800013

  • Appenroth KJ, Sree KS, Bog M, Ecker J, Böhm V, Lorkowski S, Sommer K, Vetter W, Tolzin-Banasch K, Kirmse R, Leiterer M, Dawczynski C, Liebisch G, Jahreis G. Nutritional value of the duckweed species of the genus Wolffia (Lemnaceae) as human food. Frontiers in Chemistry 2018; 6(10):483.
    DOI 10.3389/fchem.2018.00483

  • Pein H, Ville A, Pace S, Temml V, Garscha U, Raasch M, Alsabil K, Viault G, Dinh CP, Guilet D, Troisi F, Neukirch K, König S, Bilancia R, Waltenberger B, Stuppner H, Wallert M, Lorkowski S, Weinigel C, Rummler S, Birringer M, Roviezzo F, Sautebin L, Helesbeux JJ, Séraphin D, Mosig A, Schuster D, Rossi A, Richomme P, Werz O, Koeberle A. Endogenous metabolites of vitamin E limit inflammation by targeting 5-lipoxygenase. Nature Communications 2018; 9(1):3834.
    DOI 10.1038/s41467-018-06158-5

  • Heller T, Kloos C, Lehmann T, Schiel R, Lorkowski S, Wolf G, Müller UA, Müller N. Mortality and its causes in a German cohort with diabetes mellitus type 1 after 20 years of follow-up: the JEVIN trial. Experimental and Clinical Endocrinology and Diabetes 2018; 126(6):387-393.
    DOI 10.1055/s-0043-113452

  • Schmölz L, Schubert M, Kirschner J, Kluge S, Galli F, Birringer M, Wallert M, Lorkowski S. Long-chain metabolites of vitamin E: Interference with lipotoxicity via lipid droplet associated protein PLIN2. Biochimica et Biophysica Acta 2018; 1863(8):919-927.
    DOI 10.1016/j.bbalip.2018.05.002

  • Kleber ME, Delgado G, Dawczynski C, Lorkowski S, März W, von Schacky C. Saturated fatty acids and mortality in patients referred for coronary angiography - The Ludwigshafen Risk and Cardiovascular Health Study. Journal of Clinical Lipidology 2018; 12(2):455-463.
    DOI 10.1016/j.jacl.2018.01.007

  • Dawczynski C, Dittrich M, Neumann T, Goetze K, Welzel A, Oelzner P, Völker S, Schaible AM, Troisi F, Thomas L, Pace S, Koeberle A, Werz O, Schlattmann P, Lorkowski S, Jahreis G. Docosahexaenoic acid in the treatment of rheumatoid arthritis: A double-blind, placebo-controlled, randomized cross-over study with microalgae vs. sunflower oil. Clinical Nutrition 2018; 37(2):494-504.
    DOI 10.1016/j.clnu.2017.02.021

  • Irmscher S, Döring N, Halder LD, Jo EAH, Kopka I, Dunker C, Jacobsen IS, Luo S, Slevogt H, Lorkowski S, Beyersdorf N, Zipfel PF, Skerka C. Kallikrein cleaves C3 and activates complement. Journal of Innate Immunity 2018; 10(2):94-105.
    DOI 10.1159/000484257

  • Trautvetter U, Camarinha-Silva A, Jahreis G, Lorkowski S, Glei M. High phosphorous intake and gut-related parameters – results of a randomized placebo-controlled human intervention study. Nutrition Journal 2018; 17(1):23.
    DOI 10.1186/s12937-018-0331-4

  • Bratzke F, Ritschel F, Wache R, Thamm K, Kühn J, Dawczynski C, Wiacek C, Stangl GI, Braun PB, Lorkowski S, Meier T. Lebensmittel mit gesundheitsfördernden Inhaltsstoffen im deutschen Lebensmitteleinzelhandel. Ernährungs Umschau 2018; 65(1):2-11.
    An English version of this article was published as follows:
    Bratzke F, Ritschel F, Wache R, Thamm K, Kühn J, Dawczynski C, Wiacek C, Stangl GI, Braun PB, Lorkowski S, Meier T. Lebensmittel mit gesundheitsfördernden Inhaltsstoffen im deutschen Lebensmitteleinzelhandel. Ernährungs Umschau international 2018; 65(1):M14-M23.
    DOI 10.4455/eu.2018.002

  • Marx K, Meier-Gräwe U, Lorkowski S, Dawczynski C, Brombach C. Die familiäre Essumgebung im ersten Lebensjahr. Bedarfe und Ansätze für ernährungsbezogene Maßnahmen in benachteiligten Familien. Prävention und Gesundheitsförderung 2018; 13(1):69-75.
    DOI 10.1007/s11553-017-0592-3

  • Schlörmann W, Fischer S, Lamberty J, Ludwig D, Lorkowski S, Glei M. Chemopreventive potential of in vitro fermented raw and roasted hazelnuts in LT97 colon adenoma cells. Anticancer Research 2018; 38(1):83-93.
    DOI 10.21873/anticanres.12195

  • Schlörmann W, Fischer S, Lorkowski S, Saupe C, Glei M. Influence of roasting on the chemopreventive potential of in vitro fermented almonds in LT97 colon adenoma cells. International Journal of Food Sciences and Nutrition 2018; 69(1):52-63.
    DOI 10.1080/09637486.2017.1334140

 

Original Publications / Originalpublikationen Global Burden of Disease
  • GBD 2016 Lifetime Risk of Stroke Collaborators, Feigin VL, Nguyen G, Cercy K, Johnson CO, Alam T, Parmar PG, Abajobir AA, Abate KH, Abd-Allah F, Abejie AN, Abyu GY, Ademi Z, Agarwal G, Ahmed MB, Akinyemi RO, Al-Raddadi R, Aminde LN, Amlie-Lefond C, Ansari H, Asayesh H, Asgedom SW, Atey TM, Ayele HT, Banach M, Banerjee A, Barac A, Barker-Collo SL, Bärnighausen T, Barregard L, Basu S, Bedi N, Behzadifar M, Béjot Y, Bennett DA, Bensenor IM, Berhe DF, Boneya DJ, Brainin M, Campos-Nonato IR, Caso V, Castañeda-Orjuela CA, Rivas JC, Catalá-López F, Christensen H, Criqui MH, Damasceno A, Dandona L, Dandona R, Davletov K, de Courten B, deVeber G, Dokova K, Edessa D, Endres M, Faraon EJA, Farvid MS, Fischer F, Foreman K, Forouzanfar MH, Gall SL, Gebrehiwot TT, Geleijnse JM, Gillum RF, Giroud M, Goulart AC, Gupta R, Gupta R, Hachinski V, Hamadeh RR, Hankey GJ, Hareri HA, Havmoeller R, Hay SI, Hegazy MI, Hibstu DT, James SL, Jeemon P, John D, Jonas JB, Jóźwiak J, Kalani R, Kandel A, Kasaeian A, Kengne AP, Khader YS, Khan AR, Khang YH, Khubchandani J, Kim D, Kim YJ, Kivimaki M, Kokubo Y, Kolte D, Kopec JA, Kosen S, Kravchenko M, Krishnamurthi R, Kumar GA, Lafranconi A, Lavados PM, Legesse Y, Li Y, Liang X, Lo WD, Lorkowski S, Lotufo PA, Loy CT, Mackay MT, Abd El Razek HM, Mahdavi M, Majeed A, Malekzadeh R, Malta DC, Mamun AA, Mantovani LG, Martins SCO, Mate KK, Mazidi M, Mehata S, Meier T, Melaku YA, Mendoza W, Mensah GA, Meretoja A, Mezgebe HB, Miazgowski T, Miller TR, Ibrahim NM, Mohammed S, Mokdad AH, Moosazadeh M, Moran AE, Musa KI, Negoi RI, Nguyen M, Nguyen QL, Nguyen TH, Tran TT, Nguyen TT, Anggraini Ningrum DN, Norrving B, Noubiap JJ, O’Donnell MJ, Olagunju AT, Onuma OK, Owolabi MO, Parsaeian M, Patton GC, Piradov M, Pletcher MA, Pourmalek F, Prakash V, Qorbani M, Rahman M, Rahman MA, Rai RK, Ranta A, Rawaf D, Rawaf S, Renzaho AM, Robinson SR, Sahathevan R, Sahebkar A, Salomon JA, Santalucia P, Santos IS, Sartorius B, Schutte AE, Sepanlou SG, Shafieesabet A, Shaikh MA, Shamsizadeh M, Sheth KN, Sisay M, Shin MJ, Shiue I, Silva DAS, Sobngwi E, Soljak M, Sorensen RJD, Sposato LA, Stranges S, Suliankatchi RA, Tabarés-Seisdedos R, Tanne D, Nguyen CT, Thakur JS, Thrift AG, Tirschwell DL, Topor-Madry R, Tran BX, Nguyen LT, Truelsen T, Tsilimparis N, Tyrovolas S, Ukwaja KN, Uthman OA, Varakin Y, Vasankari T, Venketasubramanian N, Vlassov VV, Wang W, Werdecker A, Wolfe CDA, Xu G, Yano Y, Yonemoto N, Yu C, Zaidi Z, El Sayed Zaki M, Zhou M, Ziaeian B, Zipkin B, Vos T, Naghavi M, Murray CJL, Roth GA. Global, regional, and country-specific lifetime risks of stroke, 1990 and 2016. New England Journal of Medicine 2018; 379(25):2429-2437.
    DOI 10.1056/NEJMoa1804492

  • GBD 2017 Mortality Collaborators. Global, regional, and national age-sex-specific mortality and life expectancy, 1950-2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet 2018; 392(10159):1684-1735.
    DOI 10.1016/S0140-6736(18)31891-9

  • GBD 2017 Causes of Death Collaborators. Global, regional, and national age-sex-specific mortality for 282 causes of death in 195 countries and territories, 1980–2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet 2018; 392(10159):1736-1788.
    DOI 10.1016/S0140-6736(18)32203-7

  • GBD 2017 Disease and Injury Incidence and Prevalence Collaborators. Global, regional, and national incidence, prevalence, and years lived with disability for 354 diseases and injuries for 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet 2018; 392(10159):1789-1858.
    DOI 10.1016/S0140-6736(18)32279-7

  • GBD 2017 DALYs and HALE Collaborators. Global, regional, and national disability-adjusted life-years (DALYs) for 359 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet 2018; 392(10159):1859-1922.
    DOI 10.1016/S0140-6736(18)32335-3

  • GBD 2017 Risk Factor Collaborators. Global, regional, and national comparative risk assessment of 84 behavioural, environmental and occupational, and metabolic risks or clusters of risks for 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet 2018; 392(10159):1923-1994.
    DOI 10.1016/S0140-6736(18)32225-6

  • GBD 2017 Population and Fertility Collaborators. Population and fertility by age and sex for 195 countries and territories, 1950-2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet 2018; 392(10159):1995-2051.
    DOI 10.1016/S0140-6736(18)32278-5

  • GBD 2017 SDG Collaborators. Measuring progress from 1990 to 2017 and projecting attainment to 2030 of the health-related Sustainable Development Goals for 195 countries and territories: a systematic analysis for the Global Burden of Disease Study 2017. Lancet 2018; 392(10159):2091-2138.
    DOI 10.1016/S0140-6736(18)32281-5

  • GBD 2016 Alcohol Collaborators. Alcohol use and attributable disease burden in 195 countries and territories, 1990-2016: a systematic analysis of the Global Burden of Disease Study 2016. Lancet 2018; 392(10152):1015-1035.
    DOI 10.1016/S0140-6736(18)31310-2

  • GBD 2016 Healthcare Access and Quality Collaborators. Measuring performance on the Healthcare Access and Quality Index for 195 countries and territories and selected subnational locations: a systematic analysis from the Global Burden of Disease Study 2016. Lancet 2018; 391(10136):2236-2271.
    DOI 10.1016/S0140-6736(18)30994-2

 

Scientific Reviews / Wissenschaftliche Übersichtsarbeiten
  • Wallert M, Lorkowski S. Relevanz einer Supplementation mit Mikronährstoffen für die Herzgesundheit. Ernährung und Medizin 2018; 33(04):158-163.
    DOI 10.1055/a-0682-0670

  • Richter M, Egert S, Watzl B, Lorkowski S, for the German Nutrition Society. Das PURE Desaster: Vorschnelle Schlagzeilen führen zu unnötiger Verunsicherung von Verbrauchern und Patienten. Aktuelle Ernährungsmedizin 2018; 43(03):173-177.
    DOI 10.1055/a-0603-2782

  • Keller AA, Maeß MB, Schnoor M, Scheiding B, Lorkowski S. Transfecting macrophages. Methods in Molecular Biology 2018; 1784:187-195.
    DOI 10.1007/978-1-4939-7837-3_18

  • Birringer M, Siems K, Maxones A, Frank J, Lorkowski S. Natural 6-hydroxy-chromanols and -chromenols: structural diversity, biosynthetic pathways and health implications. RSC Advances 2018; 9:4803-4841.
    DOI 10.1039/c7ra11819h

  • Schubert M., Kluge S, Schmölz L, Wallert M, Galli F, Birringer M, Lorkowski S. Long-chain metabolites of vitamin E: metabolic activation as a general concept for lipid-soluble vitamins? Antioxidants 2018; 7(1):10.
    DOI 10.3390/antiox7010010

 

Editorials, Comments, Short Reports, Letters to the Editor etc.
  • Lorkowski S, Richter M, Linseisen J, Watzl B; for the German Nutrition Society. Is the message of PURE really so pure? The PURE study results are over-simplified and misleading. Lancet 2018; 391(10131): 1678-1679.
    DOI 10.1016/S0140-6736(18)30800-6

  • Kleber ME, Delgado GE, Dawczynski C, Lorkowski S, März W. Fat and mortality: Each fatty acid tells its own story. Lancet 2018; 391(10131):1680-1681.
    DOI 10.1016/S0140-6736(18)30798-0

 

Book Contributions / Buchbeiträge
  • Schmölz L, Schubert M, Kluge S, Birringer M, Wallert M, Lorkowski S. The hepatic fate of vitamin E. In: Vitamin E in Health and Disease. Morales-González JA, ed. IntechOpen, London, UK 2018:1-29.
    DOI 10.5772/intechopen.79445

  • Matthäus C, Chernenko T, Stiebing C, Quintero L, Miljković M, Milane L, Kale A, Amiji M, Lorkowski S, Torchilin V, Popp J, Diem M. Raman micro-spectral imaging of cells and intracellular drug delivery using nanocarrier systems. In: Confocal Raman Microscopy. Series in Surface Sciences, 2nd Edition. Toporski J, Dieing T, Hollricher O, eds. Springer, Heidelberg 2018:273-305.
    DOI 10.1007/978-3-319-75380-5_13
2017 Inhalt einblenden
Original Publications / Originalpublikationen (peer-reviewed)
  • Glei M, Ludwig D, Lamberty J, Fischer S, Lorkowski S, Schlörmann W. Chemopreventive potential of raw and roasted pistachios regarding colon carcinogenesis. Nutrients 2017; 9(12):1368.
    DOI 10.3390/nu9121368

  • Schmölz L, Wallert M, Rozzino N, Cignarella A, Galli F, Glei M, Werz O, Koeberle A, Birringer M, Lorkowski S. Structure-function relationship studies in vitro reveal distinct and specific effects of long-chain metabolites of vitamin E. Molecular Nutrition and Food Research 2017; 61(12):1700561.
    DOI 10.1002/mnfr.201700562

  • Schuett K, Kleber ME, Scharnagl H, Lorkowski S, März W, Niessner A, Marx N, Meinitzer A. Trimethylamine-N-oxide (TMAO) and heart failure with reduced versus preserved ejection fraction. Journal of the American College of Cardiology 2017; 70(25):3202-3204.
    DOI 10.1016/j.jacc.2017.10.064

  • Schlörmann W, Dinc T, Lorkowski S, Glei M. Influence of roasting on the chemopreventive potential of macadamia nuts. SDRP Journal of Food Science & Technology 2017; 2(1):1-9.
    DOI 10.25177/JFST.2.1.5

  • Schlörmann W, Lamberty J, Ludwig D, Lorkowski S, Glei M. In vitro-fermented raw and roasted walnuts induce expression of CAT and GSTT2 genes, growth inhibition and apoptosis in LT97 colon adenoma cells. Nutrition Research 2017; 47:72-80.
    DOI 10.1016/j.nutres.2017.09.004

  • Rennert K, Nitschke M, Wallert M, Keune N, Raasch M, Lorkowski S, Mosig AS. Thermo-responsive cell culture carrier – effects on macrophage functionality and detachment efficiency. Journal of Tissue Engineering 2017; 8:1-17.
    DOI 10.1177/2041731417726428

  • Schmölz L, Wallert M, Lorkowski S. Optimized incubation regime for nitric oxide measurements in murine macrophages using the Griess assay. Journal of Immunological Methods 2017; 449:68-70.
    DOI 10.1016/j.jim.2017.06.012

  • Delgado GE, März W, Lorkowski S, von Schacky C, Kleber ME. Omega-6 Fatty Acids: diverging associations with risk – The Ludwigshafen Risk and Cardiovascular Health Study. Journal of Clinical Lipidology 2017; 11(4):1082-1090.
    DOI 10.1016/j.jacl.2017.05.003

  • Stiebing C, Meyer T, Rimke I, Matthäus C, Schmitt M, Lorkowski S*, Popp J.* Real-time Raman and SRS imaging of living human macrophages reveals cell-to-cell heterogeneity and dynamics of lipid uptake. Journal of Biophotonics 2017; 10(9):1217-1226. *Contributed equally.
    DOI 10.1002/jbio.201600279
    This article ws highlighted at AdvancedScienceNews.com:
    www.advancedsciencenews.com/spontaneous-stimulated-combined-raman-imaging-reveals-news-heart-diseases
  • Lange K, Lautenschläger C, Wallert M, Lorkowski S, Stallmach A, Schiller A. Development of an advanced diagnostic concept for intestinal inflammation: Molecular visualisation of nitric oxide in macrophages by functional poly(lactic-co-glycolic acid) microspheres. Beilstein Journal of Nanotechnology 2017; 8:1637-1641.
    DOI 10.3762/bjnano.8.163

  • Giusepponi D, Torquato P, Bartolini D, Piroddi M, Birringer M, Lorkowski S, Libetta C, Cruciani G, Moretti S, Saluti G, Galli F, Galarini R. Determination of tocopherols and their metabolites by liquid-chromatography coupled with tandem mass spectrometry in human plasma and serum. Talanta 2017; 170: 552-561.
    DOI 10.1016/j.talanta.2017.04.030

  • Stiebing C, Schmölz L, Wallert M, Matthäus C, Lorkowski S*, Popp J.* Raman spectroscopic imaging of human macrophages incubated with triglyceride-enriched oxLDL visualizes translocation of lipids between endocytic vesicles and lipid droplets. Journal of Lipid Research 2017; 58(5):876-883. *Contributed equally.
    DOI 10.1194/jlr.M071688

  • Delgado G, Krämer B, Lorkowski S, März W, von Schacky C, Kleber ME. Individual omega-9 monounsaturated fatty acids and mortality - The Ludwigshafen Risk and Cardiovascular Health Study. Journal of Clinical Lipidology 2017; 11(1):126-135.
    DOI 10.1016/j.jacl.2016.10.015

  • Schlörmann W, Lamberty, Lorkowski S, Ludwig D, Mothes H, Saupe C, Glei M. Chemopreventive potential of in vitro fermented nuts in LT79 colon adenoma and primary colon cells: modulation of antioxidant and cell cycle relevant genes, proliferation and apoptosis. Molecular Carcinogenesis 2017; 56(5):1461-1471.
    DOI 10.1055/s-0042-117717

  • Heller T, Reise K, Roth J, Lehmann T, Schiel R, Lorkowski S, Müller UA, Müller N. Changes in quality of diabetes care and morbidity over 20 years in people with type 1 diabetes and long diabetes duration: The JEVIN trial. Experimental and Clinical Endocrinology and Diabetes 2017; 152(2):122-129.
    DOI 10.1055/s-0042-117717

  • Rohde A, Lorkowski S, Dawczynski C, Brombach C. Ernährungs-Apps: Akzeptanz von jungen Erwachsenen - eine qualitative Studie. Ernährungs Umschau 2017; 64(2):36-43.
    An English version of this article was published as follows:
    Rohde A, Lorkowski S, Dawczynski C, Brombach C. Dietary mobile apps: Acceptance of young adults – a qualitative approach. Ernährungs Umschau international 2017; 64(2):M76-M83.
    DOI 10.4455/eu.2017.00

  • Halder LD, Abdelfatah MA, Jo EAH, Jacobsen ID, Westermann M, Beyersdorf N, Lorkowski S, Zipfel PF, Skerka C. Factor H binds to extracellular DNA traps released from human blood monocytes in response to Candida albicans. Frontiers in Immunology 2017; 7:671.
    DOI 10.3389/fimmu.2016.00671

  • Russo A, Bartolini D, Torquato P, Giusepponi D, Barola C, Galarini R, Birringer M, Lorkowski S, Galli F. CYP4F2 repression and a modified alpha-tocopherol (vitamin E) metabolism are two independent consequences of ethanol toxicity in human hepatocytes. Toxicology in Vitro 2017; 40:124-133.
    DOI 10.1016/j.tiv.2016.12.014

  • Micklisch S, Lin Y, Jacob S, Karlstetter M, Dannhausen K, Dasari P, von der Heide M, Dahse HM, Schmölz L, Grassmann F, Alene M, Fauser S, Neumann H, Lorkowski S, Pauly D, Weber BBH, Joussen AM, Langmann T, Zipfel PF, Skerka C. Age-related macular degeneration associated polymorphism rs10490924 in ARMS2 results in deficiency of a complement activator. Journal of Neuroinflammation 2017; 14(1):4.
    DOI 10.1186/s12974-016-0776-3

 

Original Publications / Originalpublikationen Global Burden of Disease
  • GBD 2016 Mortality Collaborators. Global, regional, and national under-5 mortality, adult mortality, age-specific mortality, and life expectancy, 1970-2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet 2017; 390(10100):1084-1150.
    DOI 10.1016/S0140-6736(17)31833-0

  • GBD 2016 Causes of Death Collaborators. Global, regional, and national age-sex specific mortality for 264 causes of death, 1980-2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet 2017; 390(10100):1151-1210.
    DOI 10.1016/S0140-6736(17)32152-9

  • GBD 2016 Disease and Injury Incidence and Prevalence Collaborators. Global, regional, and national incidence, prevalence, and years lived with disability for 328 diseases and injuries for 195 countries, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet 2017; 390(10100):1211-1259.
    DOI 10.1016/S0140-6736(17)32154-2

  • GBD 2016 DALYs and HALE Collaborators. Global, regional, and national disability-adjusted life-years (DALYs) for 333 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet 2017; 390(10100):1260-1344.
    DOI 10.1016/S0140-6736(17)32130-X

  • GBD 2016 Risk Factors Collaborators. Global, regional, and national comparative risk assess-ment of 84 behavioural, environmental and occupational, and metabolic risks or clusters of risks, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet 2017; 390(10100):1345-1422.
    DOI 10.1016/S0140-6736(17)32366-8

  • GBD 2016 SDG Collaborators. Measuring progress and projecting attainment on the basis of past trends of the health-related Sustainable Development Goals in 188 countries: an analysis from the Global Burden of Disease Study 2016. Lancet 2017; 390(10100):1423-1459.
    DOI 10.1016/S0140-6736(17)32336-X

 

Scientific Reviews / Wissenschaftliche Übersichtsarbeiten
  • Volkhardt I, Christen O, Stangl GI, Braun PG, Lorkowski S, Meier T. Rechtliche Aspekte bei Produktinnovationen im Lebensmittelbereich. Ernährungs Umschau 2017; 64(11):M614-M621.
    An English version of this article was published as follows: Volkhardt I, Christen O, Stangl GI, Braun PG, Lorkowski S, Meier T. Legal aspects regarding product innovations in the food sector. Ernährungs Umschau international 2017; 64(11):158-165.
    DOI 10.4455/eu.2017.042

  • Lorkowski S. Ernährungsempfehlungen 2020: Quo vadis, Nahrungsfette? Ernährungs Umschau 2017; 64(2):M104-M107.

  • Dawczynski C, Lorkowski S. Ernährung im Alter bei Herz-Kreislauf-Erkrankungen. VFEDaktuell 2017; 157:6-11.

  • Moderne Ernährung heute, Kompendium wissenschaftlicher Pressedienste, Hrsg. Matissek R, Lebensmittelchemisches Institut (LCI) des Bundesverbandesder Deutschen Süßwarenindustrie e.V. (BDSI), Köln, 2017.

Editorials, Comments, Short Reports, Letters to the Editor etc.
  • Schwingshackl L, Knüppel S, Schwedhelm C, Hoffmann G, Missbach B, Stelmach-Mardas M, Dietrich S, Eichelmann F, Kontopantelis E, Iqbal K, Aleksandrova K, Lorkowski S, Leitzmann MF, Kroke A, Boeing H. Reply to the letter to the editor by Meehrpohl et al. on: NutriGrade: A scoring system to assess and judge the meta-evidence of randomized controlled trials and cohort studies in nutrition research. Advances in Nutrition 2017; 8(5):790-791.
    DOI 10.3945/an.117.016469
2016 Inhalt einblenden
Original Publications / Originalpublikationen (peer-reviewed)
  • Schwingshackl L, Knüppel S, Schwedhelm C, Hoffmann G, Missbach B, Stelmach-Mardas M, Dietrich S, Eichelmann F, Kontopantelis E, Iqbal K, Aleksandrova K, Lorkowski S, Leitzmann MF, Kroke A, Boeing H. NutriGrade: A scoring system to assess and judge the meta-evidence of randomized controlled trials and cohort studies in nutrition research. Advances in Nutrition 2016; 7(6):994-1004.
    DOI 10.3945/an.116.013052
    An erratum was published for this article as follows: Adv Nutr 2017; 8(2):399.
    DOI 10.3945/an.117.015206

  • Schlörmann W, Birringer M, Lochner A, Lorkowski S, Richter I, Rohrer C, Glei M. In vitro fermentation of nuts results in the formation of butyrate and c9,t11 conjugated linoleic acid as chemopreventive metabolites. European Journal of Nutrition 2016; 55(6):2063-2073.
    DOI 10.1007/s00394-015-1020-0

  • Delgado G, Kleber ME, Lorkowski S, März W, von Schacky C. Omega-3 fatty acids and mortality in patients referred for coronary angiography – The Ludwigshafen Risk and Cardiovascular Health Study. Atherosclerosis 2016; 252:175-181.
    DOI 10.1016/j.atherosclerosis.2016.06.049

  • Kramer G, Kuniß N, Jörgens V, Lehmann T, Müller N, Lorkowski S, Wolf G, Müller UA, Kloos C. Prospective analysis of principles and frequency of self-adjustment of insulin dose in people with diabetes type 1 before and after participation in a diabetes treatment and teaching programme. Diabetes Research and Clinical Practice 2016; 119:65-70.
    DOI 10.1016/j.diabres.2016.07.002

  • Delgado G, Kleber ME, Lorkowski S, März W, von Schacky C. Data on gender and subgroup specific analyses of omega-3 fatty acids in the Ludwigshafen Risk and Cardiovascular Health study. Data in Brief 2016; 8:1311-1321.
    DOI 10.1016/j.dib.2016.07.051

  • Alsabil K, Suor-Cherer S, Koeberle A, Viault G, Lavaud A, Temml V, Waltenberger B, Schuster D, Litaudon M, Lorkowski S, de Vaumas R, Helesbeux JJ, Guilet D, Stuppner H, Werz O, Seraphin D, Richomme P. Semisynthetic and natural garcinoic acid isoforms as new mPGES-1 inhibitors. Planta Medica 2016; 82(11-12):1110-1116.
    DOI 10.1055/s-0042-108739

  • Kramer G, Kuniß N, Kloos C, Lehmann T, Müller N, Wolf G, Lorkowski S, Müller UA. Principles and frequency of self-adjustment of insulin dose in people with diabetes mellitus type 1 and correlation with markers of metabolic control. Diabetes Research and Clinical Practice 2016; 116:299-305.
    DOI 10.1016/j.diabres.2016.04.025

  • Kuniß N, Kramer G, Müller N, Kloos C, Lorkowski S, Wolf G, Müller UA. Diabetes-related burden and distress is low in people with diabetes at outpatient tertiary care level. Experimental and Clinical Endocrinology and Diabetes 2016; 124(5):307-312.
    DOI 10.1055/s-0042-103685

  • Kramer G, Kuniß N, Kloos C, Lehmann T, Müller N, Sanow B, Lorkowski S, Wolf G, Müller UA. Principles of self-adjustment of insulin dose in people with diabetes type 2 and flexible insulin therapy. Diabetes Research and Clinical Practice 2016; 116:165-170.
    DOI 10.1016/j.diabres.2016.04.017

  • Rennert K, Heisig K, Gröger M, Wallert M, Funke H, Lorkowski S, Huber O, Mosig S. Recruitment of CD16+ monocytes to endothelial cells in response to LPS-treatment and concomitant TNF release is regulated by CX3CR1 and interfered by soluble fractalkine. Cytokine 2016; 83:41-52.
    DOI 10.1016/j.cyto.2016.03.017

  • Kleber ME, Delgado G, Lorkowski S, März W, von Schacky C. Trans fatty acids and mortality in patients referred for coronary angiography: the Ludwigshafen Risk and Cardiovascular Health Study. European Heart Journal 2016; 37(13):1072-1078.
    DOI 10.1093/eurheartj/ehv446
    A comment on this article was published as follows:
    Mozaffarian D. Natural trans fat, dairy fat, partially hydrogenated oils, and cardiometabolic health: the Ludwigshafen Risk and Cardiovascular Health Study. European Heart Journal 2015; 37(13):1079-1081.
    DOI 10.1093/eurheartj/ehv595

 

Scientific Reviews / Wissenschaftliche Übersichtsarbeiten
  • Schlörmann W, Müller AK, Lorkowski S, Glei M. Nüsse – Kleiner Snack mit großer Wirkung. Moderne Ernährung heute 2016; 5:1-14.
    The article was reprinted in:
    Moderne Ernährung heute, Kompendium wissenschaftlicher Pressedienste, Hrsg. Matissek R, Lebensmittelchemisches Institut (LCI) des Bundesverbandesder Deutschen Süßwarenindustrie e.V. (BDSI), Köln, 2017.

  • Dinter J, Leschik-Bonnet E, Heseker H, Wolfram G, Lorkowski S. trans-Fettsäuren und ihr Einfluss auf die Gesundheit: Teil 2. DGE info 2016; 06:86-89.

  • Dinter J, Leschik-Bonnet E, Heseker H, Wolfram G, Lorkowski S. trans-Fettsäuren und ihr Einfluss auf die Gesundheit: Teil 1 – Entstehung und Vorkommen. DGE info 2016; 05:66-68.

  • Torquato P, Ripa O, Giusepponi D, Galarini R, Bartolini D, Wallert M, Pellegrino R, Cruciani G, Lorkowski S, Birringer M, Mazzini F, Galli F. Analytical strategies to assess the functional metabolome of vitamin E. Journal of Pharmaceutical and Biomedical Analysis 2016; 124: 399-412.
    DOI 10.1016/j.jpba.2016.01.056

  • Schmölz L, Birringer M, Lorkowski S*, Wallert M*. The complexity of vitamin E metabolism. World Journal of Biological Chemistry 2016; 7(1):14-43. *Contributed equally.
    DOI 10.4331/wjbc.v7.i1.00

 

Editorials, Comments, Short Reports, Letters to the Editor etc.
  • Dawczynski C, Lorkowski S. Trans fatty acids and cardiovascular risk: Does origin matter? Expert Review of Cardiovascular Therapy 2016; 14(9):1001-1005.
    DOI 10.1080/14779072.2016.1199956
    Invited special report

 

Guidelines, Recommendations & Reference Values / Leitlinien, Empfehlungen & Referenzwerte
  • Dinter J, Bechthold A, Boeing H, Ellinger S, Leschik-Bonnet E, Linseisen J, Lorkowski S, Wolfram G. Fischverzehr und Prävention ausgewählter ernährungsmitbedingter Krankheiten. Ernährungs Umschau 2016; 63(7):M394-M400.
    An English version of this article was published as follows: Dinter J, Bechthold A, Boeing H, Ellinger S, Leschik-Bonnet E, Linseisen J, Lorkowski S, Wolfram G. Fish intake and prevention of selected nutrition-related diseases. Ernährungs Umschau international 2016; 63(7):148-154.
    DOI 10.4455/eu.2016.032
2015 Inhalt einblenden
Original Publications / Originalpublikationen (peer-reviewed)
  • Ciffolilli S, Wallert M, Krauth V, Werz O, Bartolini D, Piroddi M, Sebastiani B, Lorkowski* S, Birringer* M, Galli* G. Human serum determination and in vitro anti-inflammatory activity of vitamin E α-(13’-hydroxy)-6-hydroxychroman metabolite. Free Radical Biology and Medicine 2015; 89:952-962. *Contributed equally.
    DOI 10.1016/j.freeradbiomed.2015.08.019

  • Wallert M, Schmölz L, Koeberle A, Krauth V, Glei M, Galli F, Werz O, Birringer M, Lorkowski S. The α-tocopherol long-chain metabolite α-13'-COOH affects the inflammatory response of lipopolysaccharide-activated murine RAW264.7 macrophages. Molecular Nutrition and Food Research 2015; 59(8):1524-1534.
    DOI 10.1002/mnfr.201400737

  • Scherer O, Maeß MB, Lindner S, Garscha U, Weinigel C, Rummler S, Werz O, Lorkowski S. A procedure for efficient non-viral siRNA transfection of primary human monocytes using nucleofection. Journal of Immunological Methods 2015; 422:118-124.
    DOI 10.1016/j.jim.2015.04.007

  • Maeß MB, Keller AA, Rennert K, Mosig A, Lorkowski S. Optimization of the transfection of human THP-1 macrophages by application of Nunc UpCell technology. Analytical Biochemistry 2015; 479:40-42.
    DOI 10.1016/j.ab.2014.12.023

  • Raasch M, Rennert K, Jahn T, Peters S, Henkel T, Huber O, Schulz I, Becker H, Lorkowski S, Funke H, Mosig A. Microfluidically supported biochip design for culture of endothelial cell layers with improved perfusion conditions. Biofabrication 2015; 7(1):015013.
    DOI 10.1088/1758-5090/7/1/015013

  • Schlörmann W, Birringer M, Böhm V, Löber K, Jahreis G, Lorkowski S, Müller AK, Schöne F, Glei M. Influence of roasting conditions on health related compounds in different nuts. Food Chemistry 2015; 180:77-85.
    DOI 10.1016/j.foodchem.2015.02.017

 

Scientific Reviews / Wissenschaftliche Übersichtsarbeiten
  • Dawczynski C, Lorkowski S. Bedeutung der Nahrungsfettsäuren: Prävention kardiovaskulärer Erkrankungen. CARDIOVASC 2015; 15(6):38-46.
    DOI 10.1007/s15027-015-0660-6
    Article includes a CME-certified questionnaire.

  • Stark H, Fichtner M, König R, Lorkowski S, Schuster S. Causes of upregulation of glycolysis in lymphocytes upon stimulation: A comparison with other cell types. Biochimie 2015; 118:185-194.
    DOI 10.1016/j.biochi.2015.09.017

 

Editorials, Comments, Short Reports, Letters to the Editor etc.
  • Dawczynski C, Kleber ME, März W, Jahreis G, Lorkowski S. Saturated fatty acids are not off the hook. Nutrition, Metabolism and Cardiovascular Diseases 2015; 25(12):1071-1078.
    DOI 10.1016/j.numecd.2015.09.010

 

Guidelines, Recommendations & Reference Values / Leitlinien, Empfehlungen & Referenzwerte
  • Wolfram G, Bechthold A, Boeing H, Ellinger S, Hauner H, Kroke A, Leschik-Bonnet E, Linseisen J, Lorkowski S, Schulze M, Stehle P, Dinter J. Evidence-based guideline of the German Nutrition Society: Fat intake and prevention of selected nutrition-related diseases. Annals of Nutrition and Metabolism 2015; 67(3):141-204.
    DOI 10.1159/000437243
    This article was listed among the “Top 10 Articles” by Annals of Nutrition and Metabolism in November 2015.

  • Bechtold A, Dinter J. Evidenzbasierte Leitlinie: Fett­zufuhr und Prävention ausgewählter ernährungsmitbedingter Krankheiten. Leitlinie Fett kompakt. Deutsche Gesellschaft für Ernährung e.V. (Ed.), Bonn 2015. Wissenschaftliche Beratung: Bechthold A, Boeing H, Dinter J, Ellinger S, Hauner H, Kroke A, Leschik-Bonnet E, Linseisen J, Lorkowski S, Schulze M, Stehle P, Wolfram G.

  • Referenzwerte für die Nährstoffzufuhr. Deutsche Gesellschaft für Ernährung (DGE) e.V., Österreichische Gesellschaft für Ernährung, Schweizerische Gesellschaft für Ernährung, ed., Bonn 2015. Wissenschaftliche Beratung

  • Bechthold A, Boeing H, Dinter J, Ellinger S, Hauner H, Kroke A, Leschik-Bonnet E, Linseisen J, Lorkowski S, Schulze M, Stehle P, Wolfram G. Evidenzbasierte Leitlinie: Fettzufuhr und Prävention ausgewählter ernährungsmitbedingter Krankheiten. Deutsche Gesellschaft für Ernährung e.V., ed., Bonn 2015.
    Chapter: Lorkowski S, Boeing H, Wolfram G. Kapitel 6: Fettzufuhr und Prävention der Dys­lipo­proteinämie. Evidenzbasierte Leitlinie: Fettzufuhr und Prävention ausgewählter ernährungs­mit­bedingter Krankheiten. Deutsche Gesellschaft für Ernährung e.V., ed., Bonn 2015.
älter Inhalt einblenden
Original Publications / Originalpublikationen (peer-reviewed)
  • Maeß MB, Wittig B, Lorkowski S. Highly efficient transfection of human THP-1 macrophages by Nucleofection. Journal of Visualized Experiments 2014; (91):e51960.
    DOI 10.3791/51960

  • Jaudszus A, Lorkowski S, Grün M, Roth A, Jahreis G. Limited applicability of GW9662 to elucidate PPARγ-mediated fatty acid effects in primary human T-helper cells. International Journal of Inflammation 2014; 2014:149628.
    DOI 10.1155/2014/149628

  • Stiebing C, Matthäus C, Krafft C, Keller AA, Weber K, Lorkowski S*, Popp J.* Complexity of fatty acid distribution inside human macrophages on single cell level using Raman micro-spectroscopy. Analytical and Bioanalytical Chemistry 2014; 406(27):7037-7446. *Contributed equally.
    DOI 10.1007/s00216-014-7927-0

  • Maeß MB, Wittig B, Cignarella A, Lorkowski S. Reduced PMA enhances the responsiveness of transfected THP-1 macrophages to polarizing stimuli. Journal of Immunological Methods 2014; 402(1-2):76-81.
    DOI 10.1016/j.jim.2013.11.006

  • Wallert M, Rennert K, Mosig S, Funke H, Ristow M, Pellegrino RM, Cruciani G, Galli F, Lorkowski S*, Birringer M.* Long-chain metabolites of α-tocopherol occur in human serum and inhibit macrophage foam cell formation in vitro. Free Radical Biology and Medicine 2014; 68(C):43-51. *Contributed equally.
    DOI 10.1016/j.freeradbiomed.2013.11.009

  • Keller AA, Breitling R, Hemmerich P, Kappe K, Braun M, Wittig B, Schaefer B, Lorkowski S, Reissmann S. Transduction of proteins into Leishmania tarentolae by formation of non-covalent complexes with cell-penetrating peptides. Journal of Cellular Biochemistry 2013; 115(2):243-252.
    DOI 10.1002/jcb.24654

  • Boehme C, Bieber F, Linnemann J, Breitling R, Lorkowski S, Reissmann S. Chemical and enzymatic characterization of recombinant rabbit muscle pyruvate kinase. Biological Chemistry 2013; 394(5):695-701.
    DOI 10.1515/hsz-2012-0334

  • Keller AA, Mussbach F, Breitling R, Hemmerich P, Schaefer B, Lorkowski S, Reissmann S. Relationships between cargo, cell penetrating peptides and cell type for uptake of non-covalent complexes into live cells. Pharmaceuticals 2013; 6(2):184-203.
    DOI 10.3390/ph6020184

  • Maeß MB, Stolle K, Cullen P, Lorkowski S. Evidence for an alternative genomic structure, mRNA and protein sequence of human ABCA13. Gene 2013; 515(2):298-307.
    DOI 10.1016/j.gene.2012.11.072

  • Matthäus C, Krafft, C Dietzek B, Brehm BR, Lorkowski S*, Popp J.* Noninvasive imaging of intracellular lipid metabolism in macrophages by Raman microscopy in combination with stable isotopic labeling. Analytical Chemistry 2012; 84(20):8549-8556. *Contributed equally.
    DOI 10.1021/ac3012347
    This article was awarded with the silver WITec Paper Award 2013.

  • Maeß MB, Buers I, Robenek H, Lorkowski S. Improved protocol for efficient non-viral transfection of premature THP-1 macrophages. Cold Spring Harbor Protocols 2011; 2011(5):508-511.
    DOI 10.1101/pdb.prot5612

  • Rauch U, Saxena A, Lorkowski S, Rauterberg J, Durbeej-Hjalt M, Hultgårdh-Nilsson A. Laminin isoforms in atherosclerotic arteries from mice and man. Histology and Histopathology 2011; 26(6):711-724.

  • Maeß MB, Sendelbach S, Lorkowski S. Selection of reliable reference genes during THP-1 monocyte differentiation into macrophages. BMC Molecular Biology 2010; 11:90.
    DOI 10.1186/1471-2199-11-90
    This article was highlighted by BMC Molecular Biology as ‘highly accessed’.

  • Beetz N, Harrison M, Brede M, Zong X, Moura E, Lorkowski S, Viera-Coelho MA, Hamet P, Gaudet D, Kotchen T, Kaldunski M, Nüsing R, Biel M, Coley A, Stoll M, Lohse MJ, Broeckel U, Hein L. Phosducin influences sympathetic activity and prevents stress-induced hypertension in humans and mice. Journal of Clinical Investigation 2009; 119(12):3597-3612.
    DOI 10.1172/JCI38433
    A comment on this article was published as follows: Grassi G. Phosducin - a candidate gene for stress-dependent hypertension. Journal of Clinical Investigation 2009; 119(12):3515-3518.
    DOI 10.1172/JCI41508
    A corrigendum of this article was published as follows: Journal of Clinical Investigation 2011; 121(1):454.
    DOI 10.1172/JCI45819

  • Lorkowski S, Rauterberg J, Harrach-Ruprecht B, Troyer D. Collagen-bound LDL modifies endothelial cell adhesion to type V. Central European Journal of Biology 2009; 4(4):536-542.
    DOI 10.2478/s11535-009-0047-8
    A preliminary version of this article was pulished earlier as follows: Lorkowski S, Rauterberg J, Harrach-Ruprecht B, Troyer D. Collagen-bound low density lipoprotein modifies endothelial cell adhesion to type V collagen: Implications for atherosclerosis. (no peer-review) Nature Precedings 2007; 1-4.
    DOI 10.1038/npre.2007.1238.1

  • Robenek H, Buers I, Hofnagel O, Lorkowski S, Severs NJ. GFP-tagged proteins visualized by freeze-fracture immuno-electron microscopy: a new tool in cellular and molecular medicine. Journal of Cellular and Molecular Medicine 2009; 13(7):1381-1390.
    DOI 10.1111/j.1582-4934.2008.00407.x

  • Schnoor M, Buers I, Sietmann A, Brodde M, Hofnagel O, Robenek H, Lorkowski S. Efficient nonviral transfection of THP-1 cells. Journal of Immunological Methods 2009; 344(2):109-115.
    DOI 10.1016/j.jim.2009.03.014

  • Buers I, Robenek H, Lorkowski S, Nitschke Y, Severs NJ, Hofnagel O. TIP47, a lipid cargo protein involved in macrophage triglyceride metabolism. Arteriosclerosis, Thrombosis and Vascular Biology 2009; 29(5):767-773.
    DOI 10.1161/ATVBAHA.108.182675

  • Tölle M, Pawlak A, Schuchardt M, Kawamura A, Tietge UJ, Lorkowski S, Keul P, Assmann G, Chun J, Levkau B, van der Giet M, Nofer JR. HDL-associated lysosphingolipids Inhibit NAD(P)H oxidase-dependent monocyte chemoattractant protein-1 production. Arteriosclerosis, Thrombosis and Vascular Biology 2008; 28(8):1542-1548.
    DOI 10.1161/ATVBAHA.107.161042

  • Schmidt A, Bilgasem S, Lorkowski S, Vischer P, Völker W, Breithardt G, Siegel G, Buddecke E. Exogenous nitric oxide regulates activity and synthesis of vascular endothelial nitric oxide synthase. European Journal of Clinical Investigation 2008; 38(7): 476-485.
    DOI 10.1111/j.1365-2362.2008.01967.x

  • Schnoor M, Cullen P, Lorkowski J, Stolle K, Robenek H, Troyer D, Rauterberg J, Lorkowski S. Production of type VI collagen by human macrophages: a new dimension in macrophage functional heterogeneity. Journal of Immunology 2008; 180(8):5707-5719.
    DOI 10.4049/​jimmunol.180.8.5707

  • Broadbent HM, Peden JF, Lorkowski S, Goel A, Ongen H, Green F, Clarke R, Collins R, Franzosi MG, Tognoni G, Seedorf U, Rust S, Eriksson P, Hamsten A, Farrall M, Watkins H, for the PROCARDIS consortium. Susceptibility to coronary artery disease and diabetes is encoded by distinct, tightly linked, SNPs in the ANRIL locus on chromosome 9p. Human Molecular Genetics 2008; 17(6):806-814.
    DOI 10.1093/hmg/ddm352

  • Stolle K, Schnoor M, Fuellen G, Spitzer M, Cullen P, Lorkowski S. Cloning, genomic organization, and tissue-specific expression of the TGF-β1 inducible RASL11B gene. Biochimica et Biophysica Acta 2007; 1769(7-8):514-524.
    DOI 10.1016/j.bbaexp.2007.05.005

  • Uehara Y, Miura S, von Eckardstein A, Abe S, Fujii A, Matsuo Y, Rust S, Lorkowski S, Assmann G, Yamada T, Saku K. Unsaturated fatty acids suppress the expression of the ATP-binding cassette transporter G1 (ABCG1) and ABCA1 genes via an LXR/RXR responsible element. Atherosclerosis 2007; 191(1):11-21.
    DOI 10.1016/j.atherosclerosis.2006.04.018

  • Hofnagel O, Buers I, Lorkowski S, Schnoor M, Robenek H. Expression of perilipin isoforms in cell types involved in atherogenesis. Atherosclerosis 2007; 190(1):14-15.
    DOI 10.1016/j.atherosclerosis.2006.06.010

  • Xie, Q., Engel, T., Schnoor, M., Niehaus, J., Hofnagel, O., Buers, I., Cullen, P., Seedorf, U., Assmann, G., Lorkowski S. Cell surface localization of ABCG1 does not require LXR activation. Arteriosclerosis, Thrombosis and Vascular Biology 2006; 26(11):e143-e144. (letter)
    DOI 10.1161/01.ATV.0000245790.47112.b2

  • Robenek H, Hofnagel O, Buers I, Robenek MJ, Lorkowski S, Schnoor M, Heid H, Troyer D, Severs NJ. Butyrophilin controls milk fat globule secretion. Proceedings of the National Academy of Sciences of the USA 2006; 103(27):10385-10390.
    DOI 10.1073/pnas.0600795103

  • Schmidt A, Lorkowski S, Seidler D, Breithardt G, Buddecke E. TGF-β1 generates a specific multicomponent extracellular matrix in human coronary smooth muscle cells. European Journal of Clinical Investigation 2006; 36(7):473-482.
    DOI 10.1111/j.1365-2362.2006.01658.x

  • Lott PL, Mundry M, Sassenberg C, Lorkowski S, Fuellen G. Simplifying gene trees for easier comprehension. BMC Bioinformatics 2006; 7(1):231.
    DOI 10.1186/1471-2105-7-231

  • Spitzer M, Lorkowski S, Cullen P, Sczyrba A, Fuellen G. IsoSVM – Distinguishing isoforms and paralogs on the protein level. BMC Bioinformatics 2006; 7(1):110.
    DOI 10.1186/1471-2105-7-110

  • Fuellen G, Spitzer M, Cullen P, Lorkowski S. Correspondence of function and phylogeny of ABC proteins based on an automated analysis of 20 model protein data sets. Proteins: Structure, Function, and Bioinformatics 2005; 61(4):888-899.
    DOI 10.1002/prot.20616
    A figure of this article was used as cover figure of this journal issue.

  • Stolle K, Schnoor M, Fuellen G, Spitzer M, Engel T, Spener F, Cullen P, Lorkowski S. Cloning, cellular localization, genomic organization, and tissue-specific expression of the TGFβ1-inducible SMAP-5 gene. Gene 2005; 351:119-130.
    DOI 10.1016/j.gene.2005.03.012

  • Robenek H, Robenek MJ, Buers I, Lorkowski S, Hofnagel O, Troyer D, Severs NJ. Lipid droplets gain PAT family proteins by interaction with specialized plasma membrane domains. Journal of Biological Chemistry 2005; 280(28):26330-26338.
    DOI 10.1074/jbc.M413312200

  • Cignarella A, Engel T, von Eckardstein A, Kratz M, Lorkowski S, Lüken A, Assmann G, Cullen P. Pharmacological regulation of cholesterol efflux in human monocyte-derived macrophages in the absence of exogenous cholesterol acceptors. Atherosclerosis 2005; 179(2):229-236.
    DOI 10.1016/j.atherosclerosis.2004.11.005

  • Robenek, H, Lorkowski, S, Schnoor, M, Troyer D. Spatial integration of TIP47 and adipophilin in macrophage lipid bodies. Journal of Biological Chemistry 2005; 80(7):5789-5794.
    DOI 10.1074/jbc.M407194200

  • Stolle, K, Weitkamp, B, Rauterberg, J, Lorkowski, S, Cullen P. Laser-microdissection-based analysis of mRNA expression in human coronary arteries with intimal thickening. Journal of Histochemistry and Cytochemistry 2004; 52(11):1511-1518.
    DOI 10.1369/jhc.4A6289.2004

  • Hofnagel O, Lüchtenborg B, Stolle K, Lorkowski S, Eschert H, Plenz G, Robenek H. Proinflammatory cytokines regulate LOX-1 expression in vascular smooth muscle cells. Arteriosclerosis, Thrombosis and Vascular Biology 2004; 24(10):1789-1795.
    DOI 10.1161/01.ATV.0000140061.89096.2b

  • Schnoor M, Voß P, Cullen P, Böking T, Galla HJ, Galinski EA, Lorkowski S. Characterization of the compatible solute homoectoine as a potent PCR enhancer. Biochemical and Biophysical Research Communications 2004; 322(3):867-872.
    DOI 10.1016/j.bbrc.2004.07.200

  • Seedorf U, Engel T, Lüken A, Bode G, Lorkowski S, Assmann, G. Cholesterol absorption inhibitor ezetimibe blocks uptake of oxidized LDL in human macrophages. Biochemical and Biophysical Research Communications 2004; 320(4):1337-1341.
    DOI 10.1016/j.bbrc.2004.06.092

  • Engel T, Lüken A, Bode G, Hobohm U, Lorkowski S, Schlüter B, Rust S, Cullen P, Pech M, Assmann G, Seedorf U. ADP-ribosylation factor (ARF)-like 7 (ARL7) is induced by cholesterol loading and participates in apolipoprotein AI-dependent cholesterol export. FEBS Letters 2004; 566(1-3):241-246.
    DOI 10.1016/j.febslet.2004.04.048

  • Spitzer M, Fuellen G, Cullen P, Lorkowski S. VisCoSe: Visualization and comparison of consensus sequences. Bioinformatics 2004; 20(3):433-435.
    DOI 10.1093/bioinformatics/btg444

  • Fuellen G, Spitzer M, Cullen P, Lorkowski S. BLASTing proteomes, yielding phylogenies. In Silico Biology 2003; 3(3):313-319.

  • Uehara Y, Engel T, Li Z, Göpfert C, Rust S, Zhou X, Langer C, Schachtrup C, Wiekowski J, Lorkowski S, Assmann G, von Eckardstein A. Polyunsaturated fatty acids and acetoacetate down-regulate the expression of the ATP binding cassette transporter A1. Diabetes 2002; 51(10):2922-2928.
    DOI 10.2337/diabetes.51.10.2922

  • Engel T*, Lorkowski S*, Lüken A, Schlüter B, Berger G, Cullen P, Assmann G. The human ABCG4 gene is regulated by oxysterols and retinoids in human monocyte-derived macrophages. Biochemical and Biophysical Research Communications 2001; 288(2):483-488. *Contributed equally.
    DOI 10.1006/bbrc.2001.5756

  • Von Eckardstein A, Langer C, Engel T, Schaukal I, Cignarella A, Reinhardt J, Lorkowski S, Li Z, Zhou X, Cullen P, Assmann G. ATP binding cassette transporter ABC1 modulates the secretion of apolipoprotein E from human monocyte-derived macrophages. FASEB Journal 2001; 15(9):1555-1561.
    DOI 10.1096/fj.00-0798com

  • Lorkowski S, Kratz M, Wenner C, Schmidt R, Weitkamp B, Fobker M, Reinhardt J, Rauterberg J, Galinski EA, Cullen P. Expression of the ATP-binding cassette transporter gene ABCG1 (ABC8) in Tangier disease. Biochemical and Biophysical Research Communications 2001; 283(4):821-830.
    DOI 10.1006/bbrc.2001.4863

  • Wenner C, Lorkowski S, Engel T, Cullen P. Apolipoprotein E in macrophages and hepatocytes is degraded via the proteasomal pathway. Biochemical and Biophysical Research Communications 2001; 282(2):608-614.
    DOI 10.1006/bbrc.2001.4611

  • Lorkowski S*, Rust S*, Engel T, Jung E, Galinski EA, Assmann G, Cul­len P. Genomic sequence and structure of the human ABCG1 (ABC8) gene. Biochemical and Biophysical Research Communications 2001; 280(1):121-131. *Contributed equally.
    DOI 10.1006/bbrc.2000.4089

  • Lorkowski S, Ellinghaus P, Galinski EA, Assmann G, Cullen P. Use of longer extension phases to improve product yield in differential display PCR. Clinica Chimica Acta 2000; 299(1-2):199-204.
    DOI 10.1016/S0009-8981(00)00292-8

 

Scientific Reviews / Wissenschaftliche Übersichtsarbeiten
  • Wallert M, Schmölz L, Galli F, Birringer M, Lorkowski S. Regulatory metabolites of vitamin E and their putative relevance for atherogenesis. Redox Biology 2014; 2:495-503.
    DOI 10.1016/j.redox.2014.02.002

  • Lorkowski S. Senkung des Cholesterins mit alternativen Methoden – Möglich­keiten und Grenzen. MedReview 2012; 13(7):36-37.

  • Lorkowski S. Chemistry meets nutrition - Toward a systems biological description of human metabolism. Pure and Applied Chemistry 2011; 83(1):151-165.
    DOI 10.1351/PAC-CON-10-11-06

  • Lorkowski S. RASL11B (RAS-like, family 11, member B). Atlas of Genetics and Cytogenetics in Oncology and Haematology 2010; 14(4):747-750.
    DOI 10.4267/2042/44741
    atlasgeneticsoncology.org/Genes/RASL11BID44265ch4q12.html

  • Lorkowski S, Cullen P. Atherosclerosis: Pathogenesis, clinical features and treatment. Encyclopedia of Life Sciences 2007; 1-11.
    DOI 10.1002/9780470015902.a0004228

  • Lorkowski S, Cullen P. High-throughput analysis of mRNA expression: microarrays are not the whole story. Expert Opinion on Therapeutic Patents 2004; 14(3):377-403.
    DOI 10.1517/13543776.14.3.377

  • Cullen P, Baetta R, Bellosta S, Bernini F, Chinetti G, Cignarella A, von Eckardstein A, Exley A, Goddard M, Hofker M, Hurt-Camejo E, Kanters E, Kovanen P, Lorkowski S, McPheat W, Pentikäinen M, Rauterberg J, Ritchie A, Staels B, Weitkamp B, de Winther M. Rupture of the atherosclerotic plaque, does a good animal model exist? Arteriosclerosis, Thrombosis and Vascular Biology 2003; 23(4):535-542.
    DOI 10.1161/01.ATV.0000060200.73623.F8

  • Lorkowski S, Cullen P. ABCG subfamily of human ATP-binding cassette proteins. Pure and Applied Chemistry 2002; 74(11):2057-2081.
    DOI 10.1351/pac200274112057

  • Cullen P, Lorkowski S. DNA microarrays in medicine: manufacturing techniques and potential applications. Expert Opinion on Therapeutic Patents 2002; 12(12):1783-1794.
    DOI 10.1517/13543776.12.12.1783

  • Bellosta S, Bernini F, Chinetti G, Cignarella A, Cullen P, von Eckardstein A, Exley A, Freeth J, Goddard M, Hofker M, Kanters E, Kovanen P, Lorkowski S, Pentikäinen M, Printen J, Rauterberg J, Ritchie A, Staels B, Weitkamp B, de Winter M. Macrophage function and stability of the atherosclerotic plaque: Progress report of a European project. Nutrition, Metabolism and Cardiovascular Diseases 2002; 12(1):3-11.

  • Cullen P, Lorkowski S. Anwendungen der DNA-Arraytechnologie in der Laboratoriumsmedizin. Journal of Laboratory Medicine 2001; 25(11/12):469-476.
    DOI 10.1515/labm.2001.25.11-12.469

  • Cullen P, Lorkowski S. Biochips – Diagnostik in der Streichholzschachtel. MTA Dialog 2001; 2(1):4-8.

  • Lorkowski S, Cullen P. DNA-Computer – Arbeitet der Rechner von morgen mit DNA anstatt mit Silizium? KlinBiol 2001; 4:13-19.

  • Lorkowski S, Lorkowski G, Cullen P. Biochips – Das Labor in der Streichholzschachtel. Chemie in unserer Zeit 2000; 34(6):356-373.
    DOI 10.1002/1521-3781(200012)34:6<356::AID-CIUZ356>3.0.CO;2-N

  • Lorkowski S, Cullen P. Computertechnologie von morgen – DNA statt Silizium? BIOspektrum 2000; 6(4):277-279.

  • Lorkowski S, Cullen P. Der Computer von morgen – DNA statt Silizium? Journal of Laboratory Medicine 2000; 24(6/7):310-313.
    DOI 10.1515/labm.2000.24.6-7.310

  • Cullen P, Lorkowski S. Gene, Chips und Bits. Die nächste Generation der Labordiagnostik. Roche Dialog 2000; 1:21-24.

 

Editorials, Comments, Short Reports, Letters to the Editor etc.
  • Dawczynski C, Kleber ME, März W, Jahreis G, Lorkowski S. Association of dietary, circulating, and supplement fatty acids with coronary risk. Annals of Internal Medicine 2014; 161(6):453-454.
    DOI 10.7326/L14-5018-2

  • Lorkowski S. „Reis macht Herzinfarkt?” – MicroRNA als Ursache? DGE info 2012; 09:136-137.
    Invited comment

  • Lorkowski S. The ins and outs of lipid efflux. Journal of Molecular Medicine 2008; 86(2):129-134.
    DOI 10.10 07/s00109-007-0293-z
    Invited editorial

  • Lorkowski S, Cullen P. The ABC of cholesterol efflux and high-density lipoprotein formation. Current Opinion in Lipidology 2004; 15(5):611-613.
    DOI 10.1097/00041433-200410000-00017

  • Lorkowski S, Cullen P. High-density lipoprotein cholesterol levels and cholesterol efflux: a missing link? Current Opinion in Lipidology 2004; 15(1):81-84.
    DOI 10.1097/00041433-200402000-00014

  • Cullen P, Lorkowski S. Learning new tricks from an old dog: recent findings in familial hyper­cholesterolemia. Current Opinion in Lipidology 2003; 14(6):635-637.
    DOI 10.1097/00041433-200312000-00013

  • Cullen P, Lorkowski S, Schulte H, Seedorf U, Assmann G. Inflammation in atherosclerosis, not yet time for a paradigm shift? Current Opinion in Lipidology 2003; 14(3):325-328.
    DOI 10.1097/00041433-200306000-00012

  • Lorkowski S, Cullen P. Apolipoprotein E – From plasma lipids to plaque stability. Current Opinion in Lipidology 2002; 13(6):689-692.
    DOI 10.1097/00041433-200212000-00013

  • Cullen P, Lorkowski S. Peroxisome proliferator-activated receptor g still full of surprises. Current Opinion in Lipidology 2002; 13(3):335-337.
    DOI 10.1097/00041433-200206000-00014

  • Lorkowski S. Printing with DNA. Chemistry in Britain 2000; 36(10):22.

 

Books / Bücher
  • Lorkowski, S., Cullen, P., et al. Analysing gene expression. A handbook of methods: Possibilities and pitfalls. 基因表达分析手册—方法的实用性及其缺陷 (Translated Chinese Edition) Lorkowski, S., Cullen, P., eds. Chemical Industry Press, Beijing 2008.

  • Lorkowski, S., Cullen, P., et al. Analysing gene expression. A handbook of methods: Possibilities and pitfalls. Lorkowski, S., Cullen, P., eds. Wiley-VCH, Weinheim 2002.
    DOI 10.1002/352760149X

 

Book Contributions / Buchbeiträge
  • Lorkowski S. Die Polymerase-Kettenreaktion (PCR). In: Molekulare Diagnostik – Grundlagen der Molekularbiologie, Genetik und Analytik. 2nd Edition. Thiemann F, Cullen PM, Klein HG, eds. Wiley-VCH, Weinheim 2014:79-99.

  • Cullen P, Lorkowski S, Kratz M, Werner M, Marschall C, Klein HG, Goodlett D, Aebersold R, Wenner C. Gene expression: Basic concepts. In: Protein Science Encyclopedia 2008:1-95.
    DOI 10.1002/9783527610754.tt10

  • König S, Haberland J, Grote J, Zeller M, Gedig E, Fobker M, Erren M, Pursley SW, Pearl JE, Cullen P, Lorkowski S. Mass spectrometry for the detection and identification of proteins. In: Protein Science Encyclopedia 2008:638-702.
    DOI 10.1002/9783527610754.sa12

  • König S, Haberland J, Grote J, Zeller M, Gedig E, Fobker M, Erren M, Pursley SW, Pearl JE, Cullen P, Lorkowski S. Protein microarrays. In: Protein Science Encyclopedia 2008:660-670.
    DOI 10.1002/9783527610754.sa13

  • Lorkowski S, Thiemann F. Die Amplifikation von Nukleinsäuren. In: Leitfaden Molekulare Diagnostik – Grundlagen, Tipps und Tricks für die Praxis. Thiemann F, Cullen PM, Klein HG, eds. Wiley-VCH, Weinheim 2006:61-88.

  • Cullen P, Rauterberg J, Lorkowski S. The pathogenesis of atherosclerosis. In: Arteriosclerosis: Influence of Diet and Drugs. Handbook of Experimental Pharmacology. Von Eckardstein A, ed. Springer-Verlag, Heidelberg 2006:3-70.
    DOI 10.1007/3-540-27661-0_1
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